Corrigendum to: “Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers” [EBioMedicine 8 (2016) 117–131](S235239641630175X)(10.1016/j.ebiom.2016.04.032)

Anuradha Illendula, Jane Gilmour, Jolanta Grembecka, Venkata Sesha Srimath Tirumala, Adam Boulton, Aravinda Kuntimaddi, Charles Schmidt, Lixin Wang, John A. Pulikkan, Hongliang Zong, Mahmut Parlak, Cem Kuscu, Anna Pickin, Yunpeng Zhou, Yan Gao, Lauren Mishra, Mazhar Adli, Lucio H. Castilla, Roger A. Rajewski, Kevin A. JanesMonica L. Guzman, Constanze Bonifer, John H. Bushweller*

*Corresponding author for this work

Research output: Contribution to journalComment/debatepeer-review

Abstract

The authors wish to point out that, in some instances of the text in Results section 3.5, the units of ps-ns and μs-ms to define timescales of residue dynamics were inadvertently switched. “Interestingly, these changes occur both in the μs-ms timescale dynamics (principally near the benzimidazole ring) as well as on the ps-ns timescale (in the vicinity of the pyridine ring), with the latter perhaps a result of ring flipping of the pyridine ring.” should read “Interestingly, these changes occur both in the ps-ns timescale dynamics (principally near the benzimidazole ring) as well as on the μs-ms timescale (in the vicinity of the pyridine ring), with the latter perhaps a result of ring flipping of the pyridine ring.” “For Arg131, we observe increased μs-ms timescale dynamics with compound binding.” should read “For Arg131, we observe increased ps-ns timescale dynamics with compound binding.” “For Asn104, we observe an increase in ps-ns timescale dynamics with compound binding.” should read “For Asn104, we observe an increase in μs-ms timescale dynamics with compound binding.” Also, the legend for Fig. 3 contains similar inadvertent unit switching. In the legend for Fig. 3D, “Residues showing increased ps-ns timescale motion are colored red and those showing increased μs-ms timescale motion are colored blue.” should read “Residues showing increased μs-ms timescale motion are colored red and those showing increased ps-ns timescale motion are colored blue.” In the legend for Fig. 3E, “Red indicates increased ps-ns timescale motion and blue indicates increased μs-ms timescale motion.” should read “Red indicates increased μs-ms timescale motion and blue indicates increased ps-ns timescale motion.” These errors do not alter the conclusions of the paper.

Original languageEnglish (US)
Pages (from-to)188
Number of pages1
JournalEBioMedicine
Volume25
DOIs
StatePublished - Nov 2017

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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