Cortical mapping of the auditory middle latency response in the unanesthetized guinea pig

Nina Kraus*, D. Ian Smith, Joseph Grossman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

Auditory middle latency responses (MLRs) were mapped on the cortical surface of the unanesthetized guinea pig. The MLR consists of two positive peaks, designated A and C, with latencies of approximately 11 and 29 msec respectively, and a negative trough B, at 18 msec. Results suggest that each MLR component appears to have different generator sites and specific stimulus-response characteristics. The present work suggests that positive MLR components A and C have different generator sources because each component was maximally recorded from a different location over the contralateral temporal lobe. Little MLR activity was evident outside an area roughly 4 mm × 4 mm for each component.

Original languageEnglish (US)
Pages (from-to)219-226
Number of pages8
JournalElectroencephalography and Clinical Neurophysiology/ Evoked Potentials
Volume62
Issue number3
DOIs
StatePublished - Jan 1 1985

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

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