Cortically Controlled FES for Restoration and Rehabilitation of Function Following SCI in Rats

Filipe O. Barroso, Bryan Yoder, Josephine Wallner, Maria Jantz, Pablo Tostado, Evonne Pei, Vicki Tysseling, Lee E. Miller, Matthew C. Tresch*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter


We describe here our progress in developing a rat model for cortically controlled functional electrical stimulation (FES). In these experiments we are using neural activity recorded from motor cortex to drive stimulation of paralyzed muscles in order to restore voluntary motor function following spinal cord injury (SCI). We first evaluated the ability of different cortical interfaces to estimate intended movements and muscle activation, determining whether intracortical interfaces were necessary. We found that spiking activity from intracortical electrodes predicted movements with reasonable accuracy, whereas less invasive epidural electrodes performed considerably worse. We are currently evaluating the utility of these approaches to restore function following SCI as well as their ability to rehabilitate function with repeated training.

Original languageEnglish (US)
Title of host publicationBiosystems and Biorobotics
PublisherSpringer International Publishing
Number of pages4
StatePublished - 2019

Publication series

NameBiosystems and Biorobotics
ISSN (Print)2195-3562
ISSN (Electronic)2195-3570

ASJC Scopus subject areas

  • Biomedical Engineering
  • Mechanical Engineering
  • Artificial Intelligence


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