Cortically Controlled FES for Restoration and Rehabilitation of Function Following SCI in Rats

Filipe O. Barroso; Bryan Yoder; Josephine Wallner; Maria Jantz; Pablo Tostado; Evonne Pei; Vicki Tysseling; Lee E. Miller; Matthew C. Tresch

doi:10.1007/978-3-030-01845-0_187

Cortically Controlled FES for Restoration and Rehabilitation of Function Following SCI in Rats

Filipe O. Barroso, Bryan Yoder, Josephine Wallner, Maria Jantz, Pablo Tostado, Evonne Pei, Vicki Tysseling, Lee E. Miller, Matthew C. Tresch^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

We describe here our progress in developing a rat model for cortically controlled functional electrical stimulation (FES). In these experiments we are using neural activity recorded from motor cortex to drive stimulation of paralyzed muscles in order to restore voluntary motor function following spinal cord injury (SCI). We first evaluated the ability of different cortical interfaces to estimate intended movements and muscle activation, determining whether intracortical interfaces were necessary. We found that spiking activity from intracortical electrodes predicted movements with reasonable accuracy, whereas less invasive epidural electrodes performed considerably worse. We are currently evaluating the utility of these approaches to restore function following SCI as well as their ability to rehabilitate function with repeated training.

Original language	English (US)
Title of host publication	Biosystems and Biorobotics
Publisher	Springer International Publishing
Pages	931-934
Number of pages	4
DOIs	https://doi.org/10.1007/978-3-030-01845-0_187
State	Published - 2019

Publication series

Name	Biosystems and Biorobotics
Volume	21
ISSN (Print)	2195-3562
ISSN (Electronic)	2195-3570

Funding

The research has been sponsored by Senior Research Grant 340943 from the Craig H. Neilsen Foundation.

ASJC Scopus subject areas

Biomedical Engineering
Mechanical Engineering
Artificial Intelligence

Access to Document

10.1007/978-3-030-01845-0_187

Cite this

Barroso, F. O., Yoder, B., Wallner, J., Jantz, M., Tostado, P., Pei, E., Tysseling, V., Miller, L. E., & Tresch, M. C. (2019). Cortically Controlled FES for Restoration and Rehabilitation of Function Following SCI in Rats. In Biosystems and Biorobotics (pp. 931-934). (Biosystems and Biorobotics; Vol. 21). Springer International Publishing. https://doi.org/10.1007/978-3-030-01845-0_187

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abstract = "We describe here our progress in developing a rat model for cortically controlled functional electrical stimulation (FES). In these experiments we are using neural activity recorded from motor cortex to drive stimulation of paralyzed muscles in order to restore voluntary motor function following spinal cord injury (SCI). We first evaluated the ability of different cortical interfaces to estimate intended movements and muscle activation, determining whether intracortical interfaces were necessary. We found that spiking activity from intracortical electrodes predicted movements with reasonable accuracy, whereas less invasive epidural electrodes performed considerably worse. We are currently evaluating the utility of these approaches to restore function following SCI as well as their ability to rehabilitate function with repeated training.",

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AU - Barroso, Filipe O.

AU - Yoder, Bryan

AU - Wallner, Josephine

AU - Jantz, Maria

AU - Tostado, Pablo

AU - Pei, Evonne

AU - Tysseling, Vicki

AU - Miller, Lee E.

AU - Tresch, Matthew C.

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Cortically Controlled FES for Restoration and Rehabilitation of Function Following SCI in Rats

Abstract

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ASJC Scopus subject areas

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