Cost-effectiveness analysis: Design, measures, and classic example

Zhuo T. Su, Nirmish Singla, Hiten D. Patel

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Given the high and rising healthcare costs affecting many health systems worldwide, there is a clear need for health economic evaluations to inform effective strategies to reduce the economic burden of health care to patients, health systems and society. Cost-effectiveness analysis is a well-established health economic tool to assess the clinical and economic value of new health technologies. Cost-effectiveness analysis compares the costs and health outcomes of two or more competing interventions for a given health condition. Mathematical modeling is an integral part of cost-effectiveness analysis, synthesizing the best available evidence from diverse sources and allowing for sensitivity analyses to test the robustness of model findings to alternative input estimates and model assumptions. Cost-effectiveness analysis has an important role in informing health economic assessments and reimbursement decisions for new medical interventions.

Original languageEnglish (US)
Title of host publicationTranslational Urology
Subtitle of host publicationHandbook for Designing and Conducting Clinical and Translational Research
PublisherElsevier
Pages177-183
Number of pages7
ISBN (Electronic)9780323901864
ISBN (Print)9780323901871
DOIs
StatePublished - Jan 1 2024

Keywords

  • Cost-effectiveness analysis (CEA)
  • Cost-utility analysis (CUA)
  • Dominance
  • Health utility
  • Incremental cost-effectiveness ratio (ICER)
  • Quality-adjusted life year (QALY)
  • Willingness-to-pay (WTP) threshold

ASJC Scopus subject areas

  • General Agricultural and Biological Sciences
  • General Biochemistry, Genetics and Molecular Biology

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