Cotton-Wool Spots In Acquired Immunodeficiency Syndrome Compared With Diabetes Mellitus, Systemic Hypertension, and Central Retinal Vein Occlusion

Ahmad M. Mansour, Lee M. Jampol, Sanjay Logani, John Read, Dale Henderly

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

The cotton-wool spot is a common fundus funding in patients with many ocular and systemic diseases. We investigated the characteristics of cotton-wool spots in patients with four major diseases, ie, acquired immunodeficiency syndrome, diabetes mellitus, systemic hypertension, and central retinal vein occlusion, to see if any differences were detected in their number, size, or location. A composite of all the cotton-wool spots for each of these four categories was obtained by computed reconstruction to analyze variations in their distribution and size. The cotton-wool spots had a predilection for the temporal quadrants in the four categories and were smaller in patients with acquired immunodeficiency syndrome than the other groups. Patients with ischemic central retinal vein occlusion had more cotton-wool spots than the other groups. No other definite differences were detected. Cotton-wool spots seem to be a common pathway following various insults to the retina, most probably of a vaso-occlusive origin.

Original languageEnglish (US)
Pages (from-to)1074-1077
Number of pages4
JournalArchives of ophthalmology
Volume106
Issue number8
DOIs
StatePublished - Aug 1988

ASJC Scopus subject areas

  • Ophthalmology

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