Covert Hepatic Encephalopathy. Who Should Be Tested and Treated?

Steven L. Flamm*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Covert hepatic encephalopathy is a common problem in cirrhosis, affecting up to 80% of patients. It is defined as test-dependent brain dysfunction with clinical consequences in the setting of cirrhosis in patients who are not disoriented. Because it is not apparent clinically, and diagnostic testing has not been standardized, the issue has often been ignored in clinical practice. Yet, the clinical consequences are notable, including impaired quality of life, diminished work productivity, and poor driving skills.

Original languageEnglish (US)
Pages (from-to)473-485
Number of pages13
JournalClinics in liver disease
Issue number3
StatePublished - Aug 1 2015


  • Covert hepatic encephalopathy
  • Critical flicker frequency
  • Encephalapp stroop test
  • Inhibitory control test
  • Minimal hepatic encephalopathy
  • Probiotics
  • Psychometric hepatic encephalopathy score
  • Rifaximin

ASJC Scopus subject areas

  • Hepatology

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