Abstract
Introduction: Oligodendrogliomatosis is a rarely reported entity in literature associated with poor prognosis in terms of length and quality of life. In this paper, we describe oligodendrogliomatosis in a 15-year-old male who initially presented with altered mental status due to diabetic ketoacidosis. Clinical presentation: He was refractory to temozolomide initially but demonstrated disease regression with radiotherapy (XRT). More recently, he has had disease recurrence, which was stabilized with temozolomide therapy for a period of time. Conclusion: Contrary to most reports in literature, our patient has had excellent quality of life since his initial diagnosis and continues to carry good prognosis. In addition to oligodendrogliomatosis, our patient also developed multiple intracranial cavernomas secondary to radiation therapy, which have remained stable and asymptomatic.
Original language | English (US) |
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Pages (from-to) | 147-153 |
Number of pages | 7 |
Journal | Child's Nervous System |
Volume | 31 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2014 |
Keywords
- 1p19q deletion
- Chemotherapy
- Lomustine
- Oligodendrogliomatosis
- Procarbazine
- Radiation
- Radiation-induced cavernomas
- Temozolomide
- Vincristine
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Clinical Neurology