Cross-sectional imaging of perforated gallbladder

Adeel R. Seyal, Keyur Parekh, Fernanda D. Gonzalez-Guindalini, Paul Nikolaidis, Frank H Miller, Vahid Yaghmai*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Gallbladder perforation is a potentially life-threatening condition commonly seen as a complication of acute cholecystitis. Urgent surgical intervention is often needed to reduce serious morbidity and mortality. It presents a diagnostic challenge due to nonspecific symptoms, leading to a delay in diagnosis. Imaging plays a vital role in early identification of this potentially fatal condition and evaluation by more than one imaging modality may be required to make the diagnosis. Knowledge of specific and ancillary imaging findings is crucial to avoid misdiagnosis. In this article, we will review the risk factors, pathophysiology, and surgical classification of gallbladder perforation and discuss the role of multimodality imaging in its diagnosis. Differential diagnoses on imaging will also be discussed.

Original languageEnglish (US)
Pages (from-to)853-874
Number of pages22
JournalAbdominal Imaging
Issue number4
StatePublished - Jan 1 2014


  • Biliary fistula
  • Computed tomography
  • Gallbladder perforation
  • Gallstones
  • Magnetic resonance imaging
  • Ultrasound

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology


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