Crystal structure of tricyclo-DNA: An unusual compensatory change of two adjacent backbone torsion angles

Pradeep S. Pallan; Damian Ittig; Annie Héroux; Zdzislaw Wawrzak; Christian J. Leumann; Martin Egli

doi:10.1039/b716390h

Crystal structure of tricyclo-DNA: An unusual compensatory change of two adjacent backbone torsion angles

Pradeep S. Pallan, Damian Ittig, Annie Héroux, Zdzislaw Wawrzak, Christian J. Leumann, Martin Egli^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

The crystal structure of a DNA duplex with tricyclo-DNA (tc-DNA) residues explains the increased RNA affinity of tc-DNA relative to DNA and tc-DNA's superior resistance to nucleases.

Original language	English (US)
Pages (from-to)	883-885
Number of pages	3
Journal	Chemical Communications
Issue number	7
DOIs	https://doi.org/10.1039/b716390h
State	Published - 2008

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/b716390h

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title = "Crystal structure of tricyclo-DNA: An unusual compensatory change of two adjacent backbone torsion angles",

abstract = "The crystal structure of a DNA duplex with tricyclo-DNA (tc-DNA) residues explains the increased RNA affinity of tc-DNA relative to DNA and tc-DNA's superior resistance to nucleases.",

author = "Pallan, {Pradeep S.} and Damian Ittig and Annie H{\'e}roux and Zdzislaw Wawrzak and Leumann, {Christian J.} and Martin Egli",

year = "2008",

doi = "10.1039/b716390h",

language = "English (US)",

pages = "883--885",

journal = "Chemical Communications",

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T1 - Crystal structure of tricyclo-DNA

T2 - An unusual compensatory change of two adjacent backbone torsion angles

AU - Pallan, Pradeep S.

AU - Ittig, Damian

AU - Héroux, Annie

AU - Wawrzak, Zdzislaw

AU - Leumann, Christian J.

AU - Egli, Martin

PY - 2008

Y1 - 2008

N2 - The crystal structure of a DNA duplex with tricyclo-DNA (tc-DNA) residues explains the increased RNA affinity of tc-DNA relative to DNA and tc-DNA's superior resistance to nucleases.

AB - The crystal structure of a DNA duplex with tricyclo-DNA (tc-DNA) residues explains the increased RNA affinity of tc-DNA relative to DNA and tc-DNA's superior resistance to nucleases.

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UR - http://www.scopus.com/inward/citedby.url?scp=38849157057&partnerID=8YFLogxK

U2 - 10.1039/b716390h

DO - 10.1039/b716390h

M3 - Article

C2 - 18253536

AN - SCOPUS:38849157057

SN - 1359-7345

SP - 883

EP - 885

JO - Chemical Communications

JF - Chemical Communications

IS - 7

ER -

Crystal structure of tricyclo-DNA: An unusual compensatory change of two adjacent backbone torsion angles

Abstract

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