Crystal structure of tricyclo-DNA: An unusual compensatory change of two adjacent backbone torsion angles

Pradeep S. Pallan, Damian Ittig, Annie Héroux, Zdzislaw Wawrzak, Christian J. Leumann, Martin Egli*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    29 Scopus citations

    Abstract

    The crystal structure of a DNA duplex with tricyclo-DNA (tc-DNA) residues explains the increased RNA affinity of tc-DNA relative to DNA and tc-DNA's superior resistance to nucleases.

    Original languageEnglish (US)
    Pages (from-to)883-885
    Number of pages3
    JournalChemical Communications
    Issue number7
    DOIs
    StatePublished - 2008

    ASJC Scopus subject areas

    • Catalysis
    • Electronic, Optical and Magnetic Materials
    • Ceramics and Composites
    • Chemistry(all)
    • Surfaces, Coatings and Films
    • Metals and Alloys
    • Materials Chemistry

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