Crystal structure of tricyclo-DNA: An unusual compensatory change of two adjacent backbone torsion angles

Pradeep S. Pallan, Damian Ittig, Annie Héroux, Zdzislaw Wawrzak, Christian J. Leumann, Martin Egli*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

The crystal structure of a DNA duplex with tricyclo-DNA (tc-DNA) residues explains the increased RNA affinity of tc-DNA relative to DNA and tc-DNA's superior resistance to nucleases.

Original languageEnglish (US)
Pages (from-to)883-885
Number of pages3
JournalChemical Communications
Issue number7
DOIs
StatePublished - 2008

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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