Crystal structures of Trypanosoma brucei sterol 14α-demethylase and implications for selective treatment of human infections

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• Crystal structure of sterol 14-alpha demethylase (CYP51) from Trypanosoma brucei in ligand free state

  Lepesheva, G. I. (Contributor), Park, H.-W. (Contributor), Hargrove, T. Y. (Contributor), Vanhollebeke, B. (Contributor), Wawrzak, Z. (Contributor), Harp, J. M. (Contributor), Sundaramoorthy, M. (Contributor), Nes, W. D. (Contributor), Pays, E. (Contributor), Chaudhuri, M. (Contributor), Villalta, F. (Contributor) & Waterman, M. R. (Contributor), Protein Data Bank (PDB), Oct 6 2009

  DOI: 10.2210/pdb3G1Q/pdb, https://www.wwpdb.org/pdb?id=pdb_00003g1q

  Dataset

• Crystal structure of sterol 14-alpha demethylase (CYP51) from Trypanosoma brucei bound to an inhibitor N-(1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl)-4-(5-phenyl-1,3,4-oxaziazol-2-yl)benzamide

  Lepesheva, G. I. (Contributor), Park, H.-W. (Contributor), Hargrove, T. Y. (Contributor), Vanhollebeke, B. (Contributor), Wawrzak, Z. (Contributor), Harp, J. M. (Contributor), Sundaramoorthy, M. (Contributor), Nes, W. D. (Contributor), Pays, E. (Contributor), Chaudhuri, M. (Contributor), Villalta, F. (Contributor) & Waterman, M. R. (Contributor), Protein Data Bank (PDB), Nov 17 2009

  DOI: 10.2210/pdb3GW9/pdb, https://www.wwpdb.org/pdb?id=pdb_00003gw9

  Dataset