An all-RNA 64-mer hairpin ribozyme has been crystallized in a form suitable for X-ray diffraction analysis at 3.35 Å resolution. The construct contains the U39C substitution, which enhances catalytic efficiency and represents the minimal catalytic motif formed by intermolecular docking of two helix-loop-helix domains. The crystallization strategy and results are presented.
|Original language||English (US)|
|Number of pages||4|
|Journal||Acta Crystallographica - Section D Biological Crystallography|
|State||Published - Jan 1 2003|
ASJC Scopus subject areas
- Structural Biology