CSF phenylacetic acid and hostility in paranoid schizophrenia

Kym F. Faull*, Roy J. King, Jack D. Barchas, John G. Csernansky

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Lumbar cerebrospinal fluid concentrations of phenylacetic acid were significantly elevated in paranoid vs. nonparanoid schizophrenics. Further, phenylacetic acid concentrations were correlated with hostility. These results are consistent with the hypothesis that phenylethylamine, the proposed precursor of phenylacetic acid, plays a role in schizophrenia.

Original languageEnglish (US)
Pages (from-to)111-118
Number of pages8
JournalPsychiatry Research
Issue number2
StatePublished - Nov 1989


  • Cerebrospinal fluid
  • hostility
  • paranoid schizophrenia
  • phenylacetic acid

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry


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