Cuneate nucleus: the somatosensory gateway to the brain

Christopher Versteeg, Raeed H. Chowdhury, Lee E. Miller

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


Much remains unknown about the transformation of proprioceptive afferent input from the periphery to the cortex. Until recently, the only recordings from single neurons in the cuneate nucleus (CN) were from anesthetized animals. We are beginning to learn more about how the sense of proprioception is transformed as it propagates centrally. Recent recordings from microelectrode arrays chronically implanted in CN have revealed that CN neurons with muscle-like properties have a greater sensitivity to active reaching movements than to passive limb displacement, and we find that these neurons have receptive fields that resemble single muscles. In this review, we focus on the varied uses of proprioceptive input and the possible role of CN in processing this information.

Original languageEnglish (US)
Pages (from-to)206-215
Number of pages10
JournalCurrent Opinion in Physiology
StatePublished - Apr 2021

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)


Dive into the research topics of 'Cuneate nucleus: the somatosensory gateway to the brain'. Together they form a unique fingerprint.

Cite this