Cunninghamella echinulata causing fatally invasive fungal sinusitis

Robert E. LeBlanc; Zina Meriden; Deanna A. Sutton; Elizabeth H. Thompson; Dionissios Neofytos; Sean X. Zhang

doi:10.1016/j.diagmicrobio.2013.03.009

Cunninghamella echinulata causing fatally invasive fungal sinusitis

Robert E. LeBlanc^*, Zina Meriden, Deanna A. Sutton, Elizabeth H. Thompson, Dionissios Neofytos, Sean X. Zhang

^*Corresponding author for this work

Psychiatry and Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

We report a fatal case of invasive fungal sinusitis caused by Cunninghamella echinulata in a febrile, neutropenic 15-year-old male with relapsing acute leukemia. The isolate was recovered from a nasal biopsy from the right middle meatus, and microscopic examination of the tissue revealed angioinvasion and necrosis. Human infection caused by this organism has not been well documented; however, this report alerts us to its life-threatening potential.

Original language	English (US)
Pages (from-to)	506-509
Number of pages	4
Journal	Diagnostic Microbiology and Infectious Disease
Volume	76
Issue number	4
DOIs	https://doi.org/10.1016/j.diagmicrobio.2013.03.009
State	Published - Aug 2013

Keywords

Angioinvasion
Cunninghamella
Cunninghamella echinulata
Febrile neutropenia
Filamentous fungi
Invasive fungal infection
Leukemia
Sinusitis
Zygomycetes

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.diagmicrobio.2013.03.009

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title = "Cunninghamella echinulata causing fatally invasive fungal sinusitis",

abstract = "We report a fatal case of invasive fungal sinusitis caused by Cunninghamella echinulata in a febrile, neutropenic 15-year-old male with relapsing acute leukemia. The isolate was recovered from a nasal biopsy from the right middle meatus, and microscopic examination of the tissue revealed angioinvasion and necrosis. Human infection caused by this organism has not been well documented; however, this report alerts us to its life-threatening potential.",

keywords = "Angioinvasion, Cunninghamella, Cunninghamella echinulata, Febrile neutropenia, Filamentous fungi, Invasive fungal infection, Leukemia, Sinusitis, Zygomycetes",

author = "LeBlanc, {Robert E.} and Zina Meriden and Sutton, {Deanna A.} and Thompson, {Elizabeth H.} and Dionissios Neofytos and Zhang, {Sean X.}",

year = "2013",

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doi = "10.1016/j.diagmicrobio.2013.03.009",

language = "English (US)",

volume = "76",

pages = "506--509",

journal = "Diagnostic Microbiology and Infectious Disease",

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}

TY - JOUR

T1 - Cunninghamella echinulata causing fatally invasive fungal sinusitis

AU - LeBlanc, Robert E.

AU - Meriden, Zina

AU - Sutton, Deanna A.

AU - Thompson, Elizabeth H.

AU - Neofytos, Dionissios

AU - Zhang, Sean X.

PY - 2013/8

Y1 - 2013/8

N2 - We report a fatal case of invasive fungal sinusitis caused by Cunninghamella echinulata in a febrile, neutropenic 15-year-old male with relapsing acute leukemia. The isolate was recovered from a nasal biopsy from the right middle meatus, and microscopic examination of the tissue revealed angioinvasion and necrosis. Human infection caused by this organism has not been well documented; however, this report alerts us to its life-threatening potential.

AB - We report a fatal case of invasive fungal sinusitis caused by Cunninghamella echinulata in a febrile, neutropenic 15-year-old male with relapsing acute leukemia. The isolate was recovered from a nasal biopsy from the right middle meatus, and microscopic examination of the tissue revealed angioinvasion and necrosis. Human infection caused by this organism has not been well documented; however, this report alerts us to its life-threatening potential.

KW - Angioinvasion

KW - Cunninghamella

KW - Cunninghamella echinulata

KW - Febrile neutropenia

KW - Filamentous fungi

KW - Invasive fungal infection

KW - Leukemia

KW - Sinusitis

KW - Zygomycetes

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U2 - 10.1016/j.diagmicrobio.2013.03.009

DO - 10.1016/j.diagmicrobio.2013.03.009

M3 - Article

C2 - 23602784

AN - SCOPUS:84880729141

SN - 0732-8893

VL - 76

SP - 506

EP - 509

JO - Diagnostic Microbiology and Infectious Disease

JF - Diagnostic Microbiology and Infectious Disease

IS - 4

ER -

Cunninghamella echinulata causing fatally invasive fungal sinusitis

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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