Current technology in the diagnosis of developmentally related lung disorders

Aaron Hamvas*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations

Abstract

Respiratory disorders that present in the newborn period may result from structural, functional, or acquired mechanisms that limit gas exchange between the airspace and vascular bed. Exciting new imaging, gene sequencing, mass spectrometry, and molecular and cell-based techniques are enhancing our understanding of mechanisms of disease; highlighting the complexity of interactions between genes, development, and environment in the manifestation of health and disease; and becoming part of the clinical armamentarium for the care of patients. Some of these technologies and their clinical potential are briefly reviewed in this paper.

Original languageEnglish (US)
Pages (from-to)353-359
Number of pages7
JournalNeonatology
Volume101
Issue number4
DOIs
StatePublished - Jun 2012

Keywords

  • Childhood lung disease
  • Gene sequencing
  • Induced pluripotent stem cells
  • Lung development
  • Mass spectrometry

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Developmental Biology

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