Cutaneous Adverse Reactions of Anticancer Agents

Subuhi Kaul; Benjamin H. Kaffenberger; Jennifer N. Choi; Shawn G. Kwatra

doi:10.1016/j.det.2019.05.013

Cutaneous Adverse Reactions of Anticancer Agents

Subuhi Kaul, Benjamin H. Kaffenberger, Jennifer N. Choi, Shawn G. Kwatra^*

^*Corresponding author for this work

Dermatology

Research output: Contribution to journal › Review article › peer-review

18 Scopus citations

Abstract

Cutaneous adverse effects are one of the most frequently observed adverse reactions with anticancer agents. This has only intensified with newer targeted and immunologic agents that present with a wide array of drug toxicities and skin reactions. The spectrum ranges from benign, localized dermatoses to generalized, life-threatening cutaneous toxicities. Herein, the authors review the cutaneous adverse effects observed with conventional chemotherapy as well as targeted agents, including the emerging immune checkpoint inhibitors, which have been revolutionary in the treatment of many malignancies.

Original language	English (US)
Pages (from-to)	555-568
Number of pages	14
Journal	Dermatologic clinics
Volume	37
Issue number	4
DOIs	https://doi.org/10.1016/j.det.2019.05.013
State	Published - Oct 2019

Keywords

Anticancer
Chemotherapy
Cutaneous adverse effects
Drugs
Immunotherapy
Skin

ASJC Scopus subject areas

Dermatology

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10.1016/j.det.2019.05.013

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title = "Cutaneous Adverse Reactions of Anticancer Agents",

abstract = "Cutaneous adverse effects are one of the most frequently observed adverse reactions with anticancer agents. This has only intensified with newer targeted and immunologic agents that present with a wide array of drug toxicities and skin reactions. The spectrum ranges from benign, localized dermatoses to generalized, life-threatening cutaneous toxicities. Herein, the authors review the cutaneous adverse effects observed with conventional chemotherapy as well as targeted agents, including the emerging immune checkpoint inhibitors, which have been revolutionary in the treatment of many malignancies.",

keywords = "Anticancer, Chemotherapy, Cutaneous adverse effects, Drugs, Immunotherapy, Skin",

author = "Subuhi Kaul and Kaffenberger, {Benjamin H.} and Choi, {Jennifer N.} and Kwatra, {Shawn G.}",

year = "2019",

month = oct,

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language = "English (US)",

volume = "37",

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T1 - Cutaneous Adverse Reactions of Anticancer Agents

AU - Kaul, Subuhi

AU - Kaffenberger, Benjamin H.

AU - Choi, Jennifer N.

AU - Kwatra, Shawn G.

PY - 2019/10

Y1 - 2019/10

N2 - Cutaneous adverse effects are one of the most frequently observed adverse reactions with anticancer agents. This has only intensified with newer targeted and immunologic agents that present with a wide array of drug toxicities and skin reactions. The spectrum ranges from benign, localized dermatoses to generalized, life-threatening cutaneous toxicities. Herein, the authors review the cutaneous adverse effects observed with conventional chemotherapy as well as targeted agents, including the emerging immune checkpoint inhibitors, which have been revolutionary in the treatment of many malignancies.

AB - Cutaneous adverse effects are one of the most frequently observed adverse reactions with anticancer agents. This has only intensified with newer targeted and immunologic agents that present with a wide array of drug toxicities and skin reactions. The spectrum ranges from benign, localized dermatoses to generalized, life-threatening cutaneous toxicities. Herein, the authors review the cutaneous adverse effects observed with conventional chemotherapy as well as targeted agents, including the emerging immune checkpoint inhibitors, which have been revolutionary in the treatment of many malignancies.

KW - Anticancer

KW - Chemotherapy

KW - Cutaneous adverse effects

KW - Drugs

KW - Immunotherapy

KW - Skin

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DO - 10.1016/j.det.2019.05.013

M3 - Review article

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AN - SCOPUS:85069643569

SN - 0733-8635

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EP - 568

JO - Dermatologic clinics

JF - Dermatologic clinics

IS - 4

ER -

Cutaneous Adverse Reactions of Anticancer Agents

Abstract

Keywords

ASJC Scopus subject areas

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