Cutaneous lymphoid hyperplasia

William A. Caro, Elson B. Helwig*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

133 Scopus citations

Abstract

Observations on 193 patients with 225 biopsied lesions showing heavy lymphoid infiltrates in the skin are presented. Lesions of cutaneous lymphoid hyperplasia are compared with those of cutaneous malignant lymphoma, and histopathologic criteria for their separation are discussed. The benign lesions could usually be separated from the malignant ones by a higher incidence of epidermal, stromal, and vascular abnormalities and by the presence of a polymorphous cellular infiltrate of well‐differentiated cells. Lesions of cutaneous lymphoid hyperplasia fall into lymphoreticular, granulomatous, and follicular histopathologic patterns, depending on the nature of the infiltrate. The malignant potential of cutaneous lymphoid hyperplasia is low, but rare examples of the association of the malignant with the benign have been recorded.

Original languageEnglish (US)
Pages (from-to)487-502
Number of pages16
JournalCancer
Volume24
Issue number3
DOIs
StatePublished - Sep 1969

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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