Cutaneous Manifestations of Campylobacter jejuni Infection: A Case Report and Review of the Literature

Scott C. Roberts*, Samuel M. Stone, Sarah H. Sutton, John P. Flaherty

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

A 51-year-old man with active follicular lymphoma presented with several days of erythematous skin nodules on all extremities 2 weeks after a self-limited diarrheal illness. All serum immunoglobulin levels were found to be low. Blood cultures grew Campylobacter jejuni. The patient was given 1 week of azithromycin with complete resolution of his skin nodules. The literature of skin manifestations seen in active C. jejuni infection is reviewed. The majority of cases occur in immunocompromised hosts, many with low or no serum immunoglobulin levels. Postulated mechanisms include a lack of secretory immunoglobulin A in intestinal mucosa predisposing susceptible patients to translocated enteric pathogens; however, the precise pathogenesis underlying cutaneous manifestations is unknown.

Original languageEnglish (US)
Pages (from-to)61-63
Number of pages3
JournalInfectious Diseases in Clinical Practice
Volume28
Issue number2
DOIs
StatePublished - Mar 1 2020

Funding

From the Division of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, IL. Correspondence to: Scott C. Roberts, MD, 645 N Michigan Ave Suite 900, Chicago, IL 60611. E‐mail: [email protected]. This work was supported by the National Institutes of Health (5T32AI095207-07). The authors have no conflicts of interest to disclose. Informed consent was obtained from the patient. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved. ISSN: 1056-9103

Keywords

  • Campylobacter jejuni
  • erysipelas
  • hypogammaglobulinemia

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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