Cutaneous T-cell lymphoma and Staphylococcus aureus colonization

Victoria Nguyen, Richard H. Huggins, Terakeith Lertsburapa, Kimberly Bauer, Alfred Rademaker, Pedram Gerami, Joan Guitart*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

58 Scopus citations


Background: Bacterial infections are a common complication of cutaneous T-cell lymphoma (CTCL). The most common pathogen of cutaneous infections in CTCL patients is Staphylococcus aureus. Objective: The purpose of this study was to assess S aureus colonization rates among CTCL subjects compared to control subjects. Methods: Fifty subjects with CTCL, 25 psoriasis control subjects, and 25 healthy control subjects were included in this study. Culture swabs were obtained from nares and lesional skin or normal skin in the healthy controls. Results: S aureus colonization rates were 44% in CTCL subjects, 48% in psoriasis subjects, and 28% in healthy control subjects (P = .29). Limitations: The sample size was small, and the exclusion criteria resulted in an underestimation of the colonization rate. Conclusion: There was a trend for higher methicillin-sensitive S aureus colonization in the CTCL group compared with healthy control subjects. S aureus colonization may be directly related to body surface area of CTCL.

Original languageEnglish (US)
Pages (from-to)949-952
Number of pages4
JournalJournal of the American Academy of Dermatology
Issue number6
StatePublished - Dec 2008

ASJC Scopus subject areas

  • Dermatology


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