Cutaneous T-Cell Lymphomas: A Review with Emphasis on New Treatment Approaches

Christiane Querfeld*, Steven T. Rosen, Timothy M. Kuzel, Joan Guitart

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations

Abstract

Primary cutaneous T-cell lymphomas represent a wide variety of non-Hodgkin lymphomas that are characterized by a distinct clinical presentation. Advanced molecular and biological techniques have enhanced the recognition of cutaneous T-cell lymphomas. The most common subtypes of cutaneous T-cell lymphomas are the epidermotropic variants mycosis fungoides and Sézary syndrome. At present, a stage-adjusted therapy is the best concept available, since early aggressive treatment options did not improve the prognosis of patients with cutaneous T-cell lymphomas. Accurate diagnostic and clinical assessment as well as identification of prognostic factors provides a helpful basis for treatment strategies. Current medical literature on diagnosis, prognosis, and treatment is reviewed with emphasis on new biologic response-modifying treatment options.

Original languageEnglish (US)
Pages (from-to)150-161
Number of pages12
JournalSeminars in Cutaneous Medicine and Surgery
Volume22
Issue number3
DOIs
StatePublished - Sep 1 2003

ASJC Scopus subject areas

  • Surgery
  • Dermatology

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