TY - JOUR
T1 - Cutting to the pathophysiology chase
T2 - Translating cutting-edge neuroscience to rehabilitation practice in sports-related concussion management
AU - Chen, Yufen
AU - Herrold, Amy A.
AU - Gallagher, Virginia T.
AU - Reilly, James L.
AU - Parrish, Todd
AU - Breiter, Hans C.
N1 - Publisher Copyright:
Copyright ©2019 Journal of Orthopaedic & Sports Physical Therapy®.
PY - 2019/11/1
Y1 - 2019/11/1
N2 - cussion, is a common sports injury. Concussion involves physical injury to brain tissue and vascular and axonal damage that manifests as transient and often nonspecific clinical symptoms. Concussion diagnosis is challenging, and the relationship between brain injury and clinical symptoms is unclear. The purpose of this commentary was to translate cutting-edge neuroscience to rehabilitation practice. We (1) highlight potential biomarkers that may improve our understanding of concussion and its recovery, (2) explain why researchers must address the paucity of concussion research in female athletes, and (3) present female-specific factors that should be accounted for in future studies. Integrating objective, quantitative measures of concussion pathophysiology with concussion history, genetics, and genomics will help caregivers identify concussed athletes, tailor recovery protocols, and protect athletes from potential long-term effects of cumulative head impact.
AB - cussion, is a common sports injury. Concussion involves physical injury to brain tissue and vascular and axonal damage that manifests as transient and often nonspecific clinical symptoms. Concussion diagnosis is challenging, and the relationship between brain injury and clinical symptoms is unclear. The purpose of this commentary was to translate cutting-edge neuroscience to rehabilitation practice. We (1) highlight potential biomarkers that may improve our understanding of concussion and its recovery, (2) explain why researchers must address the paucity of concussion research in female athletes, and (3) present female-specific factors that should be accounted for in future studies. Integrating objective, quantitative measures of concussion pathophysiology with concussion history, genetics, and genomics will help caregivers identify concussed athletes, tailor recovery protocols, and protect athletes from potential long-term effects of cumulative head impact.
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U2 - 10.2519/jospt.2019.8884
DO - 10.2519/jospt.2019.8884
M3 - Review article
C2 - 31154951
AN - SCOPUS:85074377311
SN - 0190-6011
VL - 49
SP - 811
EP - 818
JO - Journal of Orthopaedic and Sports Physical Therapy
JF - Journal of Orthopaedic and Sports Physical Therapy
IS - 11
ER -