Cyclic AMP‐Dependent Protein Kinase Activity in Human Brain Across Age

M. J. Schmidt; L. L. Truex; B. Ghetti; A. Routtenberg

doi:10.1111/j.1471-4159.1980.tb12514.x

Cyclic AMP‐Dependent Protein Kinase Activity in Human Brain Across Age

M. J. Schmidt^*, L. L. Truex, B. Ghetti, A. Routtenberg

^*Corresponding author for this work

Psychology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Abstract: Cyclic AMP‐dependent protein kinase activity was measured in the cerebral cortex of humans 2 days to 83 years of age and in the cortex of F344 rats 3, 22, or 30 months of age. Protein kinase activity was detected in the human brain, but no age‐related differences in activity were observed in the presence or absence of cyclic AMP. Age differences were also not seen in protein kinase in the rat cerebral cortex. Enzyme activities in rat and human brain were similar.

Original language	English (US)
Pages (from-to)	261-265
Number of pages	5
Journal	Journal of Neurochemistry
Volume	35
Issue number	1
DOIs	https://doi.org/10.1111/j.1471-4159.1980.tb12514.x
State	Published - Jan 1 1980

Keywords

Aging
Cyclic AMP
Development
Human brain
Protein kinase

ASJC Scopus subject areas

Biochemistry
Cellular and Molecular Neuroscience

Access to Document

10.1111/j.1471-4159.1980.tb12514.x

Cite this

@article{d9cdd8f4c2e94fcb82f0b44cdbf48ecd,

title = "Cyclic AMP‐Dependent Protein Kinase Activity in Human Brain Across Age",

abstract = "Abstract: Cyclic AMP‐dependent protein kinase activity was measured in the cerebral cortex of humans 2 days to 83 years of age and in the cortex of F344 rats 3, 22, or 30 months of age. Protein kinase activity was detected in the human brain, but no age‐related differences in activity were observed in the presence or absence of cyclic AMP. Age differences were also not seen in protein kinase in the rat cerebral cortex. Enzyme activities in rat and human brain were similar.",

keywords = "Aging, Cyclic AMP, Development, Human brain, Protein kinase",

author = "Schmidt, {M. J.} and Truex, {L. L.} and B. Ghetti and A. Routtenberg",

year = "1980",

month = jan,

day = "1",

doi = "10.1111/j.1471-4159.1980.tb12514.x",

language = "English (US)",

volume = "35",

pages = "261--265",

journal = "Journal of Neurochemistry",

issn = "0022-3042",

publisher = "Wiley-Blackwell",

number = "1",

}

TY - JOUR

T1 - Cyclic AMP‐Dependent Protein Kinase Activity in Human Brain Across Age

AU - Schmidt, M. J.

AU - Truex, L. L.

AU - Ghetti, B.

AU - Routtenberg, A.

PY - 1980/1/1

Y1 - 1980/1/1

N2 - Abstract: Cyclic AMP‐dependent protein kinase activity was measured in the cerebral cortex of humans 2 days to 83 years of age and in the cortex of F344 rats 3, 22, or 30 months of age. Protein kinase activity was detected in the human brain, but no age‐related differences in activity were observed in the presence or absence of cyclic AMP. Age differences were also not seen in protein kinase in the rat cerebral cortex. Enzyme activities in rat and human brain were similar.

AB - Abstract: Cyclic AMP‐dependent protein kinase activity was measured in the cerebral cortex of humans 2 days to 83 years of age and in the cortex of F344 rats 3, 22, or 30 months of age. Protein kinase activity was detected in the human brain, but no age‐related differences in activity were observed in the presence or absence of cyclic AMP. Age differences were also not seen in protein kinase in the rat cerebral cortex. Enzyme activities in rat and human brain were similar.

KW - Aging

KW - Cyclic AMP

KW - Development

KW - Human brain

KW - Protein kinase

UR - http://www.scopus.com/inward/record.url?scp=0018826016&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018826016&partnerID=8YFLogxK

U2 - 10.1111/j.1471-4159.1980.tb12514.x

DO - 10.1111/j.1471-4159.1980.tb12514.x

M3 - Article

C2 - 6256477

AN - SCOPUS:0018826016

SN - 0022-3042

VL - 35

SP - 261

EP - 265

JO - Journal of Neurochemistry

JF - Journal of Neurochemistry

IS - 1

ER -

Cyclic AMP‐Dependent Protein Kinase Activity in Human Brain Across Age

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this