Cyclopentane-modified PNA improves the sensitivity of nanoparticle-based scanometric DNA detection

Jonathan K. Pokorski; Jwa Min Nam; Rafael A. Vega; Chad A. Mirkin; Daniel H. Appella

doi:10.1039/b418383e

Cyclopentane-modified PNA improves the sensitivity of nanoparticle-based scanometric DNA detection

Jonathan K. Pokorski^*, Jwa Min Nam, Rafael A. Vega, Chad A. Mirkin, Daniel H. Appella

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

trans-Cyclopentane-modified PNA has been successfully utilized as a target capture strand to improve the detection limit of a known DNA detection assay, and provide high levels of mismatch discrimination.

Original language	English (US)
Pages (from-to)	2101-2103
Number of pages	3
Journal	Chemical Communications
Issue number	16
DOIs	https://doi.org/10.1039/b418383e
State	Published - Apr 28 2005

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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title = "Cyclopentane-modified PNA improves the sensitivity of nanoparticle-based scanometric DNA detection",

abstract = "trans-Cyclopentane-modified PNA has been successfully utilized as a target capture strand to improve the detection limit of a known DNA detection assay, and provide high levels of mismatch discrimination.",

author = "Pokorski, {Jonathan K.} and Nam, {Jwa Min} and Vega, {Rafael A.} and Mirkin, {Chad A.} and Appella, {Daniel H.}",

year = "2005",

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doi = "10.1039/b418383e",

language = "English (US)",

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journal = "Chemical Communications",

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T1 - Cyclopentane-modified PNA improves the sensitivity of nanoparticle-based scanometric DNA detection

AU - Pokorski, Jonathan K.

AU - Nam, Jwa Min

AU - Vega, Rafael A.

AU - Mirkin, Chad A.

AU - Appella, Daniel H.

PY - 2005/4/28

Y1 - 2005/4/28

N2 - trans-Cyclopentane-modified PNA has been successfully utilized as a target capture strand to improve the detection limit of a known DNA detection assay, and provide high levels of mismatch discrimination.

AB - trans-Cyclopentane-modified PNA has been successfully utilized as a target capture strand to improve the detection limit of a known DNA detection assay, and provide high levels of mismatch discrimination.

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U2 - 10.1039/b418383e

DO - 10.1039/b418383e

M3 - Article

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EP - 2103

JO - Chemical Communications

JF - Chemical Communications

IS - 16

ER -

Cyclopentane-modified PNA improves the sensitivity of nanoparticle-based scanometric DNA detection

Abstract

ASJC Scopus subject areas

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