Cystic paracervical mass as an unusual sequela of graft-versus-host disease: A case report

Dana R. Gossett; F. J. Montz; Robert E. Bristow

Cystic paracervical mass as an unusual sequela of graft-versus-host disease: A case report

Dana R. Gossett, F. J. Montz, Robert E. Bristow^*

^*Corresponding author for this work

Obstetrics and Gynecology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

BACKGROUND: Bone marrow transplantation is used in the treatment of a variety of malignancies. One common sequela is graft-versus-host disease (GvHD.) CASE: A case of vaginal GvHD in a postmenopausal woman manifested as a 2-cm, cystic, paracervical mass. The patient was followed with consecutive pelvic ultrasounds and pelvic examinations until 27 months after transplantation, when the mass increased in size to 4 × 3 cm. Exploratory laparotomy with total abdominal hysterectomy revealed a 3 × 3-cm phlegmon within the proximal part of the vagina. Presumably, this resulted from vaginal GvHD, causing a midvaginal stricture with obstruction of cervical/uterine effluent. CONCLUSION: An awareness of the gynecologic manifestations of GvHD is critical for clinicians caring for women undergoing bone marrow transplantation.

Original language	English (US)
Pages (from-to)	600-602
Number of pages	3
Journal	Journal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume	47
Issue number	7
State	Published - Aug 12 2002

Keywords

Bone marrow transplantation
Graft-versus-host disease
Vaginal diseases

ASJC Scopus subject areas

Obstetrics and Gynecology
Reproductive Medicine

Cite this

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title = "Cystic paracervical mass as an unusual sequela of graft-versus-host disease: A case report",

abstract = "BACKGROUND: Bone marrow transplantation is used in the treatment of a variety of malignancies. One common sequela is graft-versus-host disease (GvHD.) CASE: A case of vaginal GvHD in a postmenopausal woman manifested as a 2-cm, cystic, paracervical mass. The patient was followed with consecutive pelvic ultrasounds and pelvic examinations until 27 months after transplantation, when the mass increased in size to 4 × 3 cm. Exploratory laparotomy with total abdominal hysterectomy revealed a 3 × 3-cm phlegmon within the proximal part of the vagina. Presumably, this resulted from vaginal GvHD, causing a midvaginal stricture with obstruction of cervical/uterine effluent. CONCLUSION: An awareness of the gynecologic manifestations of GvHD is critical for clinicians caring for women undergoing bone marrow transplantation.",

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N2 - BACKGROUND: Bone marrow transplantation is used in the treatment of a variety of malignancies. One common sequela is graft-versus-host disease (GvHD.) CASE: A case of vaginal GvHD in a postmenopausal woman manifested as a 2-cm, cystic, paracervical mass. The patient was followed with consecutive pelvic ultrasounds and pelvic examinations until 27 months after transplantation, when the mass increased in size to 4 × 3 cm. Exploratory laparotomy with total abdominal hysterectomy revealed a 3 × 3-cm phlegmon within the proximal part of the vagina. Presumably, this resulted from vaginal GvHD, causing a midvaginal stricture with obstruction of cervical/uterine effluent. CONCLUSION: An awareness of the gynecologic manifestations of GvHD is critical for clinicians caring for women undergoing bone marrow transplantation.

AB - BACKGROUND: Bone marrow transplantation is used in the treatment of a variety of malignancies. One common sequela is graft-versus-host disease (GvHD.) CASE: A case of vaginal GvHD in a postmenopausal woman manifested as a 2-cm, cystic, paracervical mass. The patient was followed with consecutive pelvic ultrasounds and pelvic examinations until 27 months after transplantation, when the mass increased in size to 4 × 3 cm. Exploratory laparotomy with total abdominal hysterectomy revealed a 3 × 3-cm phlegmon within the proximal part of the vagina. Presumably, this resulted from vaginal GvHD, causing a midvaginal stricture with obstruction of cervical/uterine effluent. CONCLUSION: An awareness of the gynecologic manifestations of GvHD is critical for clinicians caring for women undergoing bone marrow transplantation.

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Cystic paracervical mass as an unusual sequela of graft-versus-host disease: A case report

Abstract

Keywords

ASJC Scopus subject areas

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