Cystic paracervical mass as an unusual sequela of graft-versus-host disease: A case report

Dana R. Gossett, F. J. Montz, Robert E. Bristow*

*Corresponding author for this work

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

BACKGROUND: Bone marrow transplantation is used in the treatment of a variety of malignancies. One common sequela is graft-versus-host disease (GvHD.) CASE: A case of vaginal GvHD in a postmenopausal woman manifested as a 2-cm, cystic, paracervical mass. The patient was followed with consecutive pelvic ultrasounds and pelvic examinations until 27 months after transplantation, when the mass increased in size to 4 × 3 cm. Exploratory laparotomy with total abdominal hysterectomy revealed a 3 × 3-cm phlegmon within the proximal part of the vagina. Presumably, this resulted from vaginal GvHD, causing a midvaginal stricture with obstruction of cervical/uterine effluent. CONCLUSION: An awareness of the gynecologic manifestations of GvHD is critical for clinicians caring for women undergoing bone marrow transplantation.

Original languageEnglish (US)
Pages (from-to)600-602
Number of pages3
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume47
Issue number7
StatePublished - Aug 12 2002

Keywords

  • Bone marrow transplantation
  • Graft-versus-host disease
  • Vaginal diseases

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Reproductive Medicine

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