TY - JOUR
T1 - Cytokine production by mast cells and basophils
AU - Galli, Stephen J.
AU - Gordon, John R.
AU - Wershil, Barry K.
PY - 1991/12
Y1 - 1991/12
N2 - Mast cells and/or basophils have been implicated in the expression of a wide variety of biological responses, including immediate hypersensitivity reactions, host responses to parasites and neoplasms, angiogenesis, tissue remodeling, and immunologically non-specific inflammatory and fibrotic conditions. Recent findings suggest that an important mechanism by which mast cells influence such biological responses is through the production of a broad panel of multifunctional cytokines. In contrast, the extent to which basophils can produce cytokines is uncertain.
AB - Mast cells and/or basophils have been implicated in the expression of a wide variety of biological responses, including immediate hypersensitivity reactions, host responses to parasites and neoplasms, angiogenesis, tissue remodeling, and immunologically non-specific inflammatory and fibrotic conditions. Recent findings suggest that an important mechanism by which mast cells influence such biological responses is through the production of a broad panel of multifunctional cytokines. In contrast, the extent to which basophils can produce cytokines is uncertain.
UR - http://www.scopus.com/inward/record.url?scp=0026328465&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026328465&partnerID=8YFLogxK
U2 - 10.1016/S0952-7915(05)80005-6
DO - 10.1016/S0952-7915(05)80005-6
M3 - Article
C2 - 1793528
AN - SCOPUS:0026328465
SN - 0952-7915
VL - 3
SP - 865
EP - 873
JO - Current Opinion in Immunology
JF - Current Opinion in Immunology
IS - 6
ER -