Cytomegalovirus enterocolitis mimicking necrotizing enterocolitis: Case report and review of the literature

Maskit Bar-Meir*, Kathryn N. Farrow, Hector Melin-Aldana, Ellen G. Chadwick

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

A case of necrotizing enterocolitis (NEC) with pathologic evidence of cytomegalovirus (CMV) infection is presented. This preterm infant developed abdominal distention and tachycardia, and a clinical diagnosis of NEC was made. Acute bowel obstruction occurred 20 days later. Biopsy specimens of the ileum obtained during laparotomy showed extensive CMV inclusion bodies and positive immunoperoxidase staining for CMV. Urine culture and polymerase chain reaction from the blood were also positive for CMV. The patient was treated with ganciclovir and recovered. Thirty-two similar cases of CMV enterocolitis and intestinal obstruction in premature and full term babies are reviewed here.

Original languageEnglish (US)
Article numberpis060
Pages (from-to)71-75
Number of pages5
JournalJournal of the Pediatric Infectious Diseases Society
Volume2
Issue number1
DOIs
StatePublished - Mar 2013

Keywords

  • Cytomegalovirus
  • Infant
  • Necrotizing enterocolitis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Infectious Diseases

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