Cytoplasmic transcription factor sequestration drives the pathogenesis of a rearranged leukemia

Keyphrases

• Transcription Factor 100%
• Leukemia 100%
• Sequestration 100%
• Oncofusion 100%
• Super Elongation Complex 66%
• Protein chimera 66%
• Oncofusion Proteins 66%
• Gene Expression 33%
• Hematological Malignancies 33%
• Cellular Mechanisms 33%
• Chromosomal Translocation 33%
• Oncogenesis 33%
• Chromatin Binding 33%
• Gene number 33%
• Transcription Elongation 33%
• RNA Polymerase II (RNAPII) 33%
• Elongation Factor 33%
• Elongation Checkpoint 33%
• Checkpoint Control 33%
• Chimeric Protein 33%
• Sequester 33%
• Pediatric Leukemia 33%
• Cancer Pathogenesis 33%
• Transcriptional Mechanism 33%
• Encoding Gene 33%
• Runt-related Transcription Factor 1 (RUNX1) 33%
• Hijack 33%
• KMT2A 33%
• MYH1 33%

Biochemistry, Genetics and Molecular Biology

• Transcription Factors 100%
• Drive 66%
• Chromosomal Translocation 33%
• Elongation Factor 33%
• KMT2A 33%
• Core Binding Factor Beta 33%
• Gene Expression 33%
• Enhancer Region 33%
• Transcription Elongation 33%
• Carcinogenesis 33%
• RNA Polymerase II 33%
• Chimeric Protein 33%