Cytotoxic T lymphocyte recognition of non-Hodgkin's B cell lymphomas

Alan M. Krensky*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Human cytolytic T lymphocytes specific for autologous Burkitt's lymphoma express the γ,δ T cell receptor and recognize immunoglobulin idiotype in an MHC-unrestricted manner. Antibodies against a member of the heat shock protein 70 family inhibit this specific cytotoxicity, implicating these molecules in tumor recognition and antigen presentation. Such data is relevant to the design of novel immunotherapies for cancer and provides new insights into target recognition by γ,δ T cells.

Original languageEnglish (US)
Pages (from-to)91-97
Number of pages7
JournalImmunologic Research
Issue number2
StatePublished - Jun 1996


  • B cell lymphoma (non-Hodgkin's)
  • Burkitt's lymphoma
  • Cytotoxic T lymphocytes
  • Heat shock proteins
  • Immunotherapy
  • Tumor
  • γδ T cell receptor

ASJC Scopus subject areas

  • Immunology


Dive into the research topics of 'Cytotoxic T lymphocyte recognition of non-Hodgkin's B cell lymphomas'. Together they form a unique fingerprint.

Cite this