Cytotoxicity of ferrite particles by MTT and agar diffusion methods for hyperthermic application

Dong Hyun Kim, Se Ho Lee, Kyoung Nam Kim, Kwang Mahn Kim, In Bo Shim, Yong Keun Lee*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

67 Scopus citations

Abstract

We investigated the cytotoxicity of the prepared various ferrites (Fe-, Li-, Ni/Zn/Cu-, Ba-, Sr-, Co-, Co/Ni-ferrites) using MTT assay as well as agar diffusion method. Their cytotoxicity was compared with that of alginate-encapsulated ferrites. In the MTT assay, Fe3O4 and SrFe12O19 ferrite showed the highest cell viability of 90%. Alginate-encapsulated Ba-ferrite was ranked mildly cytotoxic, whereas their ferrite particles were ranked cytotoxic.

Original languageEnglish (US)
Pages (from-to)287-292
Number of pages6
JournalJournal of Magnetism and Magnetic Materials
Volume293
Issue number1
DOIs
StatePublished - May 1 2005

Keywords

  • Agar overlay assay
  • Biocompatibility
  • Co/Ni ferrite
  • Cobalt ferrite
  • Cytotoxicity
  • Ferrite
  • Hyperthermia
  • MTT assay
  • Magnetite
  • SrFeO ferrite
  • Toxicity

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

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