Deciphering the Etiologies of Adult Erythroderma: An Updated Guide to Presentations, Diagnostic Tools, Pathophysiologies, and Treatments

Yanzhen Pang, William Q. Nguyen, Liliana I. Guerrero, Lauren P. Chrisman, Madeline J. Hooper, Morgan C. McCarthy, Molly K. Hales, Rachel E. Lipman, Amy S. Paller, Joan Guitart, Xiaolong A. Zhou*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Erythroderma, an inflammatory skin condition characterized by widespread erythema with variable degrees of exfoliation, pustulation, or vesiculobullous formation, is associated with high morbidity and mortality. Determining the underlying cause of erythroderma frequently presents a diagnostic challenge, which may contribute to the condition’s relatively poor prognosis. This review covers the clinical presentation, pathophysiology, diagnosis, and treatment of erythroderma. It discusses similarities and differences among the many underlying etiologies of the condition and differences between erythrodermic and non-erythrodermic presentations of the same dermatosis. Finally, this article explores current research that may provide future tools in the diagnosis and management of erythroderma.

Original languageEnglish (US)
Pages (from-to)927-950
Number of pages24
JournalAmerican Journal of Clinical Dermatology
Volume25
Issue number6
DOIs
StatePublished - Nov 2024

ASJC Scopus subject areas

  • Dermatology

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