Decision making and management of gliomas: Practical considerations

A. F. Hottinger; K. Homicsko; L. Negretti; B. Lhermitte; R. Stupp

doi:10.1093/annonc/mds302

Decision making and management of gliomas: Practical considerations

A. F. Hottinger, K. Homicsko, L. Negretti, B. Lhermitte, R. Stupp^*

^*Corresponding author for this work

Neurological Surgery

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Over the last decade, diagnostic options and introduction of novel treatments have expanded the armamentarium in the management of malignant glioma. Combined chemoradiotherapy has become the standard of care in glioblastoma up to the age of 70 years, while treatment in elderly patients or with lower grade glioma is less well defined. Molecular markers define different disease subtypes and allow for adapted treatment selection. This review focuses on simple questions arising in the daily management of patients.

Original language	English (US)
Pages (from-to)	x33-x40
Journal	Annals of Oncology
Volume	23
Issue number	SUPPL. 10
DOIs	https://doi.org/10.1093/annonc/mds302
State	Published - Sep 2012

Keywords

Anaplastic astrocytoma
Chemotherapy
Glioblastoma
IDH1
MGMT
Oligodendroglioma

ASJC Scopus subject areas

Hematology
Oncology

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10.1093/annonc/mds302

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title = "Decision making and management of gliomas: Practical considerations",

abstract = "Over the last decade, diagnostic options and introduction of novel treatments have expanded the armamentarium in the management of malignant glioma. Combined chemoradiotherapy has become the standard of care in glioblastoma up to the age of 70 years, while treatment in elderly patients or with lower grade glioma is less well defined. Molecular markers define different disease subtypes and allow for adapted treatment selection. This review focuses on simple questions arising in the daily management of patients.",

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T2 - Practical considerations

AU - Hottinger, A. F.

AU - Homicsko, K.

AU - Negretti, L.

AU - Lhermitte, B.

AU - Stupp, R.

PY - 2012/9

Y1 - 2012/9

N2 - Over the last decade, diagnostic options and introduction of novel treatments have expanded the armamentarium in the management of malignant glioma. Combined chemoradiotherapy has become the standard of care in glioblastoma up to the age of 70 years, while treatment in elderly patients or with lower grade glioma is less well defined. Molecular markers define different disease subtypes and allow for adapted treatment selection. This review focuses on simple questions arising in the daily management of patients.

AB - Over the last decade, diagnostic options and introduction of novel treatments have expanded the armamentarium in the management of malignant glioma. Combined chemoradiotherapy has become the standard of care in glioblastoma up to the age of 70 years, while treatment in elderly patients or with lower grade glioma is less well defined. Molecular markers define different disease subtypes and allow for adapted treatment selection. This review focuses on simple questions arising in the daily management of patients.

KW - Anaplastic astrocytoma

KW - Chemotherapy

KW - Glioblastoma

KW - IDH1

KW - MGMT

KW - Oligodendroglioma

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JO - Annals of Oncology

JF - Annals of Oncology

IS - SUPPL. 10

ER -

Decision making and management of gliomas: Practical considerations

Abstract

Keywords

ASJC Scopus subject areas

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