Deep brain stimulation as an effective treatment option for post-midbrain infarction-related tremor as it presents with Benedikt syndrome: Case report

S. Kathleen Bandt, Douglas Anderson*, Jose Biller

*Corresponding author for this work

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Benedikt syndrome is a rare but debilitating constellation of symptoms that manifests from infarction of the red nucleus, cerebral peduncle, oculomotor fascicles, and lower oculomotor nucleus. Clinically, it presents as ipsilateral cranial nerve III palsy, contralateral hemiataxia with intention tremor, contralateral hemiparesis, and hyperactive tendon reflexes. Commonly, the tremor upon purposeful movement proves to be the most debilitating manifestation of the infarction with significant impact on the patient's ability to perform activities of daily living and, therefore, quality of life. The authors report the successful management of this debilitating post-midbrain infarction tremor with the insertion of a deep brain stimulator with targets in the contralateral lenticular fasciculus.

Original languageEnglish (US)
Pages (from-to)635-639
Number of pages5
JournalJournal of neurosurgery
Volume109
Issue number4
DOIs
StatePublished - Oct 1 2008

Keywords

  • Benedikt syndrome
  • Deep brain stimulation
  • Lenticular fasciculus
  • Midbrain infarction
  • Post-stroke tremor

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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