@article{1709438bc52b4b0eaede005308af8a0e,
title = "Deep sampling of Hawaiian Caenorhabditis elegans reveals high genetic diversity and admixture with global populations",
abstract = "Hawaiian isolates of the nematode species Caenorhabditis elegans have long been known to harbor genetic diversity greater than the rest of the worldwide population, but this observation was supported by only a small number of wild strains. To better characterize the niche and genetic diversity of Hawaiian C. elegans and other Caenorhabditis species, we sampled different substrates and niches across the Hawaiian islands. We identified hundreds of new Caenorhabditis strains from known species and a new species, Caenorhabditis oiwi. Hawaiian C. elegans are found in cooler climates at high elevations but are not associated with any specific substrate, as compared to other Caenorhabditis species. Surprisingly, admixture analysis revealed evidence of shared ancestry between some Hawaiian and non-Hawaiian C. elegans strains. We suggest that the deep diversity we observed in Hawaii might represent patterns of ancestral genetic diversity in the C. elegans species before human influence.",
author = "Crombie, {Tim A.} and Stefan Zdraljevic and Cook, {Daniel E.} and Tanny, {Robyn E.} and Brady, {Shannon C.} and Ye Wang and Evans, {Kathryn S.} and Steffen Hahnel and Daehan Lee and Rodriguez, {Briana C.} and Gaotian Zhang and {van der Zwagg}, Joost and Karin Kiontke and Andersen, {Erik C.}",
note = "Funding Information: We thank the members of the Andersen lab for editing the manuscript for flow and content and for making reagents used in the experiments presented. We are grateful to landowners who gave us permission to collect nematodes on their property. We also thank individuals who have helped us collect additional strains. We would also like to thank the Hawaii Department of Land and Natural Resources as well as the Natural Area Reserves System for permitting, support for these studies, and general advice about the Hawaiian Islands. Additionally, Dr. Sam Gon from The Nature Conservancy Hawai{\textquoteright}i Program helped with the naming of Caenorhabditis oiwi. This research was supported by start-up funds from Weinberg College of Arts and Sciences and the Molecular Biosciences department. KK is supported by NSF DEB 0922012 to DHA Fitch. Publisher Copyright: {\textcopyright} 2019, eLife Sciences Publications Ltd. All rights reserved.",
year = "2019",
month = dec,
doi = "10.7554/eLife.50465",
language = "English (US)",
volume = "8",
journal = "eLife",
issn = "2050-084X",
publisher = "eLife Sciences Publications",
}