Deficiency in Re-Orienting of Attention in Adults with Attention-Deficit Hyperactivity Disorder

Valentina Gumenyuk; Oleg Korzyukov; Natalie Tapaskar; Michael Wagner; Charles R. Larson; Michael J. Hammer

doi:10.1177/15500594221115737

Deficiency in Re-Orienting of Attention in Adults with Attention-Deficit Hyperactivity Disorder

Valentina Gumenyuk^*, Oleg Korzyukov, Natalie Tapaskar, Michael Wagner, Charles R. Larson, Michael J. Hammer

^*Corresponding author for this work

Communication Sciences and Disorders

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Objective: To characterize potential brain indexes of attention deficit hyperactivity disorder (ADHD) in adults. Methods: In an effort to develop objective, laboratory-based tests that can help to establish ADHD diagnosis, the brain indexes of distractibility was investigated in a group of adults. We used event-related brain potentials (ERPs) and performance measures in a forced-choice visual task. Results: Behaviorally aberrant distractibility in the ADHD group was significantly higher. Across three ERP components of distraction: N1 enhancement, P300 (P3a), and Reorienting Negativity (RON) the significant difference between ADHD and matched controls was found in the amplitude of the RON. We used non-parametric randomization tests, enabling us to statistically validated this difference between-group. Conclusions: Our main results of this feasibility study suggest that among other ERP components associated with auditory distraction, the RON response is promising index for a potential biomarker of deficient re-orienting of attention in adults s with ADHD.

Original language	English (US)
Pages (from-to)	141-150
Number of pages	10
Journal	Clinical EEG and Neuroscience
Volume	54
Issue number	2
DOIs	https://doi.org/10.1177/15500594221115737
State	Published - Mar 2023

Keywords

ERP index
auditory
distractibility in ADHD
reorienting negativity (RON)

ASJC Scopus subject areas

Neurology
Clinical Neurology

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title = "Deficiency in Re-Orienting of Attention in Adults with Attention-Deficit Hyperactivity Disorder",

abstract = "Objective: To characterize potential brain indexes of attention deficit hyperactivity disorder (ADHD) in adults. Methods: In an effort to develop objective, laboratory-based tests that can help to establish ADHD diagnosis, the brain indexes of distractibility was investigated in a group of adults. We used event-related brain potentials (ERPs) and performance measures in a forced-choice visual task. Results: Behaviorally aberrant distractibility in the ADHD group was significantly higher. Across three ERP components of distraction: N1 enhancement, P300 (P3a), and Reorienting Negativity (RON) the significant difference between ADHD and matched controls was found in the amplitude of the RON. We used non-parametric randomization tests, enabling us to statistically validated this difference between-group. Conclusions: Our main results of this feasibility study suggest that among other ERP components associated with auditory distraction, the RON response is promising index for a potential biomarker of deficient re-orienting of attention in adults s with ADHD.",

keywords = "ERP index, auditory, distractibility in ADHD, reorienting negativity (RON)",

author = "Valentina Gumenyuk and Oleg Korzyukov and Natalie Tapaskar and Michael Wagner and Larson, {Charles R.} and Hammer, {Michael J.}",

note = "Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the NIH, Foundation for the National Institutes of Health, (grant number R01DC006243, R01DC014519). Publisher Copyright: {\textcopyright} EEG and Clinical Neuroscience Society (ECNS) 2022.",

year = "2023",

month = mar,

doi = "10.1177/15500594221115737",

language = "English (US)",

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AU - Gumenyuk, Valentina

AU - Korzyukov, Oleg

AU - Tapaskar, Natalie

AU - Wagner, Michael

AU - Larson, Charles R.

AU - Hammer, Michael J.

N1 - Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the NIH, Foundation for the National Institutes of Health, (grant number R01DC006243, R01DC014519). Publisher Copyright: © EEG and Clinical Neuroscience Society (ECNS) 2022.

PY - 2023/3

Y1 - 2023/3

N2 - Objective: To characterize potential brain indexes of attention deficit hyperactivity disorder (ADHD) in adults. Methods: In an effort to develop objective, laboratory-based tests that can help to establish ADHD diagnosis, the brain indexes of distractibility was investigated in a group of adults. We used event-related brain potentials (ERPs) and performance measures in a forced-choice visual task. Results: Behaviorally aberrant distractibility in the ADHD group was significantly higher. Across three ERP components of distraction: N1 enhancement, P300 (P3a), and Reorienting Negativity (RON) the significant difference between ADHD and matched controls was found in the amplitude of the RON. We used non-parametric randomization tests, enabling us to statistically validated this difference between-group. Conclusions: Our main results of this feasibility study suggest that among other ERP components associated with auditory distraction, the RON response is promising index for a potential biomarker of deficient re-orienting of attention in adults s with ADHD.

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Deficiency in Re-Orienting of Attention in Adults with Attention-Deficit Hyperactivity Disorder

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