Defining new surrogate markers for CKD progression

H. William Schnaper*, Susan L. Furth, Lynne P. Yao

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

At a recent meeting of international experts on clinical aspects of progressive chronic kidney disease (CKD), an extensive analysis of extant clinical trials was used to develop more effective and economical surrogate markers for CKD outcomes in adults. This article describes the reasons for this undertaking, the methods and conclusions of the meeting, and the relevance of these findings to pediatric nephrology.

Original languageEnglish (US)
Pages (from-to)193-198
Number of pages6
JournalPediatric Nephrology
Volume30
Issue number2
DOIs
StatePublished - Nov 5 2015

Funding

We appreciate thoughtful comments on the manuscript by Aliza Thompson. This work was supported in part by grants R01-DK049362 (to H.W.S.), and K24-DK078737 and U01-DK066174 (to S.L.F.) from the National Institute of Diabetes, Digestive and Kidney Diseases.

Keywords

  • Chronic kidney disease
  • GFR
  • Kidney function
  • Locusta migratoria
  • Pediatric CKD
  • Surrogate markers

ASJC Scopus subject areas

  • Nephrology
  • Pediatrics, Perinatology, and Child Health

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