Defining the functional boundaries of the murine α1,3- fucosyltransferase Fut7 reveals a remarkably compact locus

Mark E. Ebel, Geoffrey Scott Kansas*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Background: Fut7 gene expression is tightly regulated and controls leukocyte traffic. Results: A 12.7 kb genomic interval controls Fut7 gene expression in all cell types. Conclusion: This interval therefore represents the functional boundaries of the Fut7 locus. Significance: All cis-acting genetic elements that control Fut7 expression are within this genomic interval.

Original languageEnglish (US)
Pages (from-to)6341-6349
Number of pages9
JournalJournal of Biological Chemistry
Volume289
Issue number10
DOIs
StatePublished - Mar 7 2014

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology
  • Molecular Biology

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