Abstract
Objective: To determine the percent reduction cutoffs on the Multidimensional Anxiety Scale for Children (MASC) that optimally predict treatment response and remission in youth with anxiety disorders. Method: Youths and their parents completed the MASC-C/P before and after treatment, and the Anxiety Disorders Interview Schedule for DSM-IV–Child and Parent Versions (ADIS-IV-C/P) and the Clinical Global Impression–Improvement Scale (CGI-I) were administered by independent evaluators. Treatment response and remission were defined by post-treatment ratings on the CGI-I and the ADIS-IV-C/P, respectively. Quality receiver operating characteristic methods determined the optimal cutoff on the MASC-P for predicting overall remission (loss of all study entry diagnoses) and optimal percent reductions on the MASC-P for predicting treatment response and remission of separation anxiety, social anxiety, and generalized anxiety. Results: A post-treatment raw score of 42 optimally predicted remission. A reduction of 35% on the total MASC-P predicted treatment response. A reduction of 30% on the Separation Anxiety/Panic subscale of the MASC-P predicted separation anxiety remission. A reduction of 35% on the Social Anxiety subscale of the MASC-P predicted social anxiety remission. The MASC did not evidence a cutoff for remission of generalized anxiety disorder. Conclusion: MASC cutoffs can facilitate comparison across studies and guide practice, aiding clinicians in assessing progress and informing treatment plans.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 418-427 |
| Number of pages | 10 |
| Journal | Journal of the American Academy of Child and Adolescent Psychiatry |
| Volume | 57 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 1 2018 |
| Externally published | Yes |
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Keywords
- Multidimensional Anxiety Scale for Children
- child anxiety
- clinical assessment
- measurement
- treatment outcome
ASJC Scopus subject areas
- Developmental and Educational Psychology
- Psychiatry and Mental health
Cite this
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Defining Treatment Response and Remission in Youth Anxiety : A Signal Detection Analysis With the Multidimensional Anxiety Scale for Children. / Palitz, Sophie A.; Caporino, Nicole E.; McGuire, Joseph F.; Piacentini, John; Albano, Anne Marie; Birmaher, Boris; Walkup, John Timothy; Compton, Scott N.; Ginsburg, Golda S.; Kendall, Philip C.
In: Journal of the American Academy of Child and Adolescent Psychiatry, Vol. 57, No. 6, 01.06.2018, p. 418-427.Research output: Contribution to journal › Article
TY - JOUR
T1 - Defining Treatment Response and Remission in Youth Anxiety
T2 - A Signal Detection Analysis With the Multidimensional Anxiety Scale for Children
AU - Palitz, Sophie A.
AU - Caporino, Nicole E.
AU - McGuire, Joseph F.
AU - Piacentini, John
AU - Albano, Anne Marie
AU - Birmaher, Boris
AU - Walkup, John Timothy
AU - Compton, Scott N.
AU - Ginsburg, Golda S.
AU - Kendall, Philip C.
PY - 2018/6/1
Y1 - 2018/6/1
N2 - Objective: To determine the percent reduction cutoffs on the Multidimensional Anxiety Scale for Children (MASC) that optimally predict treatment response and remission in youth with anxiety disorders. Method: Youths and their parents completed the MASC-C/P before and after treatment, and the Anxiety Disorders Interview Schedule for DSM-IV–Child and Parent Versions (ADIS-IV-C/P) and the Clinical Global Impression–Improvement Scale (CGI-I) were administered by independent evaluators. Treatment response and remission were defined by post-treatment ratings on the CGI-I and the ADIS-IV-C/P, respectively. Quality receiver operating characteristic methods determined the optimal cutoff on the MASC-P for predicting overall remission (loss of all study entry diagnoses) and optimal percent reductions on the MASC-P for predicting treatment response and remission of separation anxiety, social anxiety, and generalized anxiety. Results: A post-treatment raw score of 42 optimally predicted remission. A reduction of 35% on the total MASC-P predicted treatment response. A reduction of 30% on the Separation Anxiety/Panic subscale of the MASC-P predicted separation anxiety remission. A reduction of 35% on the Social Anxiety subscale of the MASC-P predicted social anxiety remission. The MASC did not evidence a cutoff for remission of generalized anxiety disorder. Conclusion: MASC cutoffs can facilitate comparison across studies and guide practice, aiding clinicians in assessing progress and informing treatment plans.
AB - Objective: To determine the percent reduction cutoffs on the Multidimensional Anxiety Scale for Children (MASC) that optimally predict treatment response and remission in youth with anxiety disorders. Method: Youths and their parents completed the MASC-C/P before and after treatment, and the Anxiety Disorders Interview Schedule for DSM-IV–Child and Parent Versions (ADIS-IV-C/P) and the Clinical Global Impression–Improvement Scale (CGI-I) were administered by independent evaluators. Treatment response and remission were defined by post-treatment ratings on the CGI-I and the ADIS-IV-C/P, respectively. Quality receiver operating characteristic methods determined the optimal cutoff on the MASC-P for predicting overall remission (loss of all study entry diagnoses) and optimal percent reductions on the MASC-P for predicting treatment response and remission of separation anxiety, social anxiety, and generalized anxiety. Results: A post-treatment raw score of 42 optimally predicted remission. A reduction of 35% on the total MASC-P predicted treatment response. A reduction of 30% on the Separation Anxiety/Panic subscale of the MASC-P predicted separation anxiety remission. A reduction of 35% on the Social Anxiety subscale of the MASC-P predicted social anxiety remission. The MASC did not evidence a cutoff for remission of generalized anxiety disorder. Conclusion: MASC cutoffs can facilitate comparison across studies and guide practice, aiding clinicians in assessing progress and informing treatment plans.
KW - Multidimensional Anxiety Scale for Children
KW - child anxiety
KW - clinical assessment
KW - measurement
KW - treatment outcome
UR - http://www.scopus.com/inward/record.url?scp=85047625182&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85047625182&partnerID=8YFLogxK
U2 - 10.1016/j.jaac.2018.03.013
DO - 10.1016/j.jaac.2018.03.013
M3 - Article
VL - 57
SP - 418
EP - 427
JO - Journal of the American Academy of Child and Adolescent Psychiatry
JF - Journal of the American Academy of Child and Adolescent Psychiatry
SN - 0890-8567
IS - 6
ER -