Democlocycline improves hyponatremia in chronic schizophrenics

Morris B. Goldman*, Daniel J. Luchins

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


Serum sodium concentration increased significantly in eight hyponatremic schizophrenic subjects treated with demeclocycline. The incidence of severe hyponatremic episodes was significantly reduced. The authors argue that mild impairments in urinary dilution contribute to water intoxication in most chronic psychotics who develop this syndrome. Demeclocycline may help these patients.

Original languageEnglish (US)
Pages (from-to)1149-1155
Number of pages7
JournalBiological psychiatry
Issue number11
StatePublished - Nov 1985

ASJC Scopus subject areas

  • Biological Psychiatry

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