TY - JOUR
T1 - Demographic, psychosocial, and behavioral factors associated with survival after heart transplantation
AU - Farmer, Steven A.
AU - Grady, Kathleen L.
AU - Wang, Edward
AU - McGee, Edwin C.
AU - Cotts, William G.
AU - McCarthy, Patrick M.
N1 - Funding Information:
This study was funded by the National Institute of Nursing Research Grant R01 NR005200 ; a grant-in-aid from the College of Nursing, Rush University ; intramural funding from the Rush Heart Institute, Rush University Medical Center; and Northwestern University, Division of Cardiac Surgery.
PY - 2013/3
Y1 - 2013/3
N2 - Background: Heart transplantation requires substantial personal, financial, and psychosocial resources. Using an existing multisite data set, we examined predictors of mortality at 5 to 10 years after heart transplantation. Methods: All 555 participants completed a self-report quality of life instrument. Of these patients, 55 (10%) died 5 to 10 years after heart transplantation. Statistical analyses included frequencies, means, Pearson correlation coefficients, and Cox proportional hazard modeling. Results: Educational level and higher levels of social and economic satisfaction were predictive of improved survival. Conversely, married status, more cumulative infections, the presence of hematologic disorders, higher New York Heart Association (NYHA) class, and poor adherence to medical care predicted worse survival. Conclusions: Demographic, clinical, psychosocial, and behavioral factors were important predictors of long-term survival after heart transplantation. These findings have important implications for patient selection for heart transplantation, as well as for posttransplantation care.
AB - Background: Heart transplantation requires substantial personal, financial, and psychosocial resources. Using an existing multisite data set, we examined predictors of mortality at 5 to 10 years after heart transplantation. Methods: All 555 participants completed a self-report quality of life instrument. Of these patients, 55 (10%) died 5 to 10 years after heart transplantation. Statistical analyses included frequencies, means, Pearson correlation coefficients, and Cox proportional hazard modeling. Results: Educational level and higher levels of social and economic satisfaction were predictive of improved survival. Conversely, married status, more cumulative infections, the presence of hematologic disorders, higher New York Heart Association (NYHA) class, and poor adherence to medical care predicted worse survival. Conclusions: Demographic, clinical, psychosocial, and behavioral factors were important predictors of long-term survival after heart transplantation. These findings have important implications for patient selection for heart transplantation, as well as for posttransplantation care.
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U2 - 10.1016/j.athoracsur.2012.11.041
DO - 10.1016/j.athoracsur.2012.11.041
M3 - Article
C2 - 23374446
AN - SCOPUS:84874641892
SN - 0003-4975
VL - 95
SP - 876
EP - 883
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 3
ER -