Demonstration of substance P immunoreactivity in the nucleus dorsalis of human spinal cord

Erik P. Pioro; J. Trevor Hughes; A. Claudio Cuello

doi:10.1016/0304-3940(84)90263-5

Demonstration of substance P immunoreactivity in the nucleus dorsalis of human spinal cord

Erik P. Pioro, J. Trevor Hughes, A. Claudio Cuello^*

^*Corresponding author for this work

Neurology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Substance P immunoreactivity has been detected in varicosities around cell bodies of the nucleus dorsalis (Clarke's column) of the human spinal cord. This immunostaining probably represents neuropeptide immunoreactivity either in the nerve terminals of spinal interneurone, descending projections or in the primary dorsal root afferents which have been shown previously to synapse with the neurones of Clarke's column. The presence of substance P immunoreactivity in the human nucleus dorsalis suggests a role of substance P in the transmission of proprioceptive and exteroceptive information from the lower trunk and limbs to the cerebellum.

Original language	English (US)
Pages (from-to)	61-65
Number of pages	5
Journal	Neuroscience Letters
Volume	51
Issue number	1
DOIs	https://doi.org/10.1016/0304-3940(84)90263-5
State	Published - Sep 28 1984

Keywords

dorsal spinocerebellar tract
nucleus dorsalis
proproception
substance P

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/0304-3940(84)90263-5

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abstract = "Substance P immunoreactivity has been detected in varicosities around cell bodies of the nucleus dorsalis (Clarke's column) of the human spinal cord. This immunostaining probably represents neuropeptide immunoreactivity either in the nerve terminals of spinal interneurone, descending projections or in the primary dorsal root afferents which have been shown previously to synapse with the neurones of Clarke's column. The presence of substance P immunoreactivity in the human nucleus dorsalis suggests a role of substance P in the transmission of proprioceptive and exteroceptive information from the lower trunk and limbs to the cerebellum.",

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AU - Pioro, Erik P.

AU - Hughes, J. Trevor

AU - Cuello, A. Claudio

PY - 1984/9/28

Y1 - 1984/9/28

N2 - Substance P immunoreactivity has been detected in varicosities around cell bodies of the nucleus dorsalis (Clarke's column) of the human spinal cord. This immunostaining probably represents neuropeptide immunoreactivity either in the nerve terminals of spinal interneurone, descending projections or in the primary dorsal root afferents which have been shown previously to synapse with the neurones of Clarke's column. The presence of substance P immunoreactivity in the human nucleus dorsalis suggests a role of substance P in the transmission of proprioceptive and exteroceptive information from the lower trunk and limbs to the cerebellum.

AB - Substance P immunoreactivity has been detected in varicosities around cell bodies of the nucleus dorsalis (Clarke's column) of the human spinal cord. This immunostaining probably represents neuropeptide immunoreactivity either in the nerve terminals of spinal interneurone, descending projections or in the primary dorsal root afferents which have been shown previously to synapse with the neurones of Clarke's column. The presence of substance P immunoreactivity in the human nucleus dorsalis suggests a role of substance P in the transmission of proprioceptive and exteroceptive information from the lower trunk and limbs to the cerebellum.

KW - dorsal spinocerebellar tract

KW - nucleus dorsalis

KW - proproception

KW - substance P

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Demonstration of substance P immunoreactivity in the nucleus dorsalis of human spinal cord

Abstract

Keywords

ASJC Scopus subject areas

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