Depression

David C. Mohr

doi:10.1201/b12666-15

Depression

David C. Mohr^*

^*Corresponding author for this work

Preventive Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Depression is common among people with multiple sclerosis (MS). The 12-month prevalence of major depressive disorder is twice that seen in the general population. This chapter reviews potential explanations for this increased prevalence, including MS pathogenic factors such as inammation; lesion volume in specific frontal, temporal, and/or parietal brain regions; genetic predisposition; and psychosocial factors. This chapter also discusses issues in diagnosis and screening of depression in MS. Finally, trials examining the efficacy of pharmacotherapy and psychotherapy for the treatment of depression in MS are reviewed. After reading this chapter, you will be able to.

Original language	English (US)
Title of host publication	Multiple Sclerosis Rehabilitation
Subtitle of host publication	From Impairment to Participation
Publisher	CRC Press
Pages	227-245
Number of pages	19
ISBN (Electronic)	9781439828854
ISBN (Print)	9781138072565
DOIs	https://doi.org/10.1201/b12666-15
State	Published - Jan 1 2012

ASJC Scopus subject areas

Medicine(all)
Neuroscience(all)

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10.1201/b12666-15

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Depression

Abstract

ASJC Scopus subject areas

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