TY - JOUR
T1 - Depressive symptoms and carotid intima–media thickness in South American Hispanics
T2 - results from the PREVENCION study
AU - Chirinos Medina, Diana Andrea
AU - Medina-Lezama, Josefina
AU - Salinas-Najarro, Belissa
AU - Arguelles, William
AU - Llabre, Maria M.
AU - Schneiderman, Neil
AU - Paz-Manrique, Roberto
AU - Bolanos, Juan F.
AU - Khan, Zubair
AU - Chirinos, Julio A.
N1 - Publisher Copyright:
© 2014, Springer Science+Business Media New York.
PY - 2015/4
Y1 - 2015/4
N2 - This study aimed to: (1) examine the relationship between depressive symptoms and subclinical atherosclerosis, measured by carotid intima–media thickness (IMT); and, (2) Determine the moderating effect of gender in this relationship among South American Hispanics. We studied 496 adults enrolled in the population-based PREVENCION study. Carotid IMT was measured with high-resolution ultrasonography. Depressive symptoms were assessed using the Hospital Anxiety and Depression Scale. Mean carotid IMT was 0.66 mm. (SD = 0.17) and mean depression score was 5.6 (SD = 3.5). Depressive symptoms were not associated with carotid IMT (β = 0.04, p = 0.222) in multivariate analyses. A significant moderating effect of gender was found (β for interaction = 0.10, p = 0.030), resulting from a significant association between depressive symptoms and carotid IMT in men but not women. Depressive symptoms were associated with subclinical atherosclerosis in South American Hispanic men but not women after controlling for demographic characteristics and traditional cardiovascular risk factors.
AB - This study aimed to: (1) examine the relationship between depressive symptoms and subclinical atherosclerosis, measured by carotid intima–media thickness (IMT); and, (2) Determine the moderating effect of gender in this relationship among South American Hispanics. We studied 496 adults enrolled in the population-based PREVENCION study. Carotid IMT was measured with high-resolution ultrasonography. Depressive symptoms were assessed using the Hospital Anxiety and Depression Scale. Mean carotid IMT was 0.66 mm. (SD = 0.17) and mean depression score was 5.6 (SD = 3.5). Depressive symptoms were not associated with carotid IMT (β = 0.04, p = 0.222) in multivariate analyses. A significant moderating effect of gender was found (β for interaction = 0.10, p = 0.030), resulting from a significant association between depressive symptoms and carotid IMT in men but not women. Depressive symptoms were associated with subclinical atherosclerosis in South American Hispanic men but not women after controlling for demographic characteristics and traditional cardiovascular risk factors.
KW - Cardiovascular disease
KW - Carotid intima–media thickness
KW - Depression
KW - Gender moderation
KW - South American Hispanics
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U2 - 10.1007/s10865-014-9599-9
DO - 10.1007/s10865-014-9599-9
M3 - Article
C2 - 25267357
AN - SCOPUS:84925463165
SN - 0160-7715
VL - 38
SP - 284
EP - 293
JO - Journal of Behavioral Medicine
JF - Journal of Behavioral Medicine
IS - 2
ER -
