Depth-resolved low-coherence enhanced backscattering

Young L. Kim, Yang Liu, Vladimir M. Turzhitsky, Ramesh K. Wali, Hemant K. Roy, Vadim Backman

Research output: Contribution to journalArticlepeer-review

40 Scopus citations

Abstract

The phenomenon of enhanced backscattering (also known as coherent backscattering), an object of substantial scientific interest, has awaited application to tissue optics for the past two decades. Here we demonstrate, for the first time to our knowledge, depth-resolved spectroscopic elastic light scattering measurements in tissue by use of low-coherence enhanced backscattering (LEBS). We achieve the depth resolution by exploiting the nature of the LEBS peak that contains information about a wide range of tissue depths. We further demonstrate that depth-resolved LEBS spectroscopy has the potential to identify the origin of precancerous transformations in the colon at an early, previously undetectable stage.

Original languageEnglish (US)
Pages (from-to)741-743
Number of pages3
JournalOptics Letters
Volume30
Issue number7
DOIs
StatePublished - Apr 1 2005

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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