Depth-resolved low-coherence enhanced backscattering

Young L. Kim; Yang Liu; Vladimir M. Turzhitsky; Ramesh K. Wali; Hemant K. Roy; Vadim Backman

doi:10.1364/OL.30.000741

Depth-resolved low-coherence enhanced backscattering

Young L. Kim, Yang Liu, Vladimir M. Turzhitsky, Ramesh K. Wali, Hemant K. Roy, Vadim Backman

Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Abstract

The phenomenon of enhanced backscattering (also known as coherent backscattering), an object of substantial scientific interest, has awaited application to tissue optics for the past two decades. Here we demonstrate, for the first time to our knowledge, depth-resolved spectroscopic elastic light scattering measurements in tissue by use of low-coherence enhanced backscattering (LEBS). We achieve the depth resolution by exploiting the nature of the LEBS peak that contains information about a wide range of tissue depths. We further demonstrate that depth-resolved LEBS spectroscopy has the potential to identify the origin of precancerous transformations in the colon at an early, previously undetectable stage.

Original language	English (US)
Pages (from-to)	741-743
Number of pages	3
Journal	Optics Letters
Volume	30
Issue number	7
DOIs	https://doi.org/10.1364/OL.30.000741
State	Published - Apr 1 2005

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics

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10.1364/OL.30.000741

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title = "Depth-resolved low-coherence enhanced backscattering",

abstract = "The phenomenon of enhanced backscattering (also known as coherent backscattering), an object of substantial scientific interest, has awaited application to tissue optics for the past two decades. Here we demonstrate, for the first time to our knowledge, depth-resolved spectroscopic elastic light scattering measurements in tissue by use of low-coherence enhanced backscattering (LEBS). We achieve the depth resolution by exploiting the nature of the LEBS peak that contains information about a wide range of tissue depths. We further demonstrate that depth-resolved LEBS spectroscopy has the potential to identify the origin of precancerous transformations in the colon at an early, previously undetectable stage.",

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AU - Kim, Young L.

AU - Liu, Yang

AU - Turzhitsky, Vladimir M.

AU - Wali, Ramesh K.

AU - Roy, Hemant K.

AU - Backman, Vadim

PY - 2005/4/1

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N2 - The phenomenon of enhanced backscattering (also known as coherent backscattering), an object of substantial scientific interest, has awaited application to tissue optics for the past two decades. Here we demonstrate, for the first time to our knowledge, depth-resolved spectroscopic elastic light scattering measurements in tissue by use of low-coherence enhanced backscattering (LEBS). We achieve the depth resolution by exploiting the nature of the LEBS peak that contains information about a wide range of tissue depths. We further demonstrate that depth-resolved LEBS spectroscopy has the potential to identify the origin of precancerous transformations in the colon at an early, previously undetectable stage.

AB - The phenomenon of enhanced backscattering (also known as coherent backscattering), an object of substantial scientific interest, has awaited application to tissue optics for the past two decades. Here we demonstrate, for the first time to our knowledge, depth-resolved spectroscopic elastic light scattering measurements in tissue by use of low-coherence enhanced backscattering (LEBS). We achieve the depth resolution by exploiting the nature of the LEBS peak that contains information about a wide range of tissue depths. We further demonstrate that depth-resolved LEBS spectroscopy has the potential to identify the origin of precancerous transformations in the colon at an early, previously undetectable stage.

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Depth-resolved low-coherence enhanced backscattering

Abstract

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