TY - JOUR
T1 - Dermatologic Uses of Methotrexate in Children
T2 - Indications and Guidelines
AU - Paller, Amy S.
PY - 1985/1/1
Y1 - 1985/1/1
N2 - Abstract: Although methotrexate is frequently employed as an antimetabolic chemotherapeutic agent for childhood cancer, it is rarely used for dermatologic disorders in children. In the pediatrie patient whose skin disease is recalcitrant to more conservative treatment, a trial of methotrexate is often appropriate. There are few reports of the drug's use for skin disorders in childhood upon which to base rational therapeutic management, however. In setting guidelines for use in children, we must consider pharmacokinetic studies and methotrexate toxicity observed in managing pediatric cancer.
AB - Abstract: Although methotrexate is frequently employed as an antimetabolic chemotherapeutic agent for childhood cancer, it is rarely used for dermatologic disorders in children. In the pediatrie patient whose skin disease is recalcitrant to more conservative treatment, a trial of methotrexate is often appropriate. There are few reports of the drug's use for skin disorders in childhood upon which to base rational therapeutic management, however. In setting guidelines for use in children, we must consider pharmacokinetic studies and methotrexate toxicity observed in managing pediatric cancer.
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U2 - 10.1111/j.1525-1470.1985.tb01059.x
DO - 10.1111/j.1525-1470.1985.tb01059.x
M3 - Article
C2 - 3887343
AN - SCOPUS:0021949973
VL - 2
SP - 238
EP - 243
JO - Pediatric Dermatology
JF - Pediatric Dermatology
SN - 0736-8046
IS - 3
ER -