Dermatomyositis without creatine kinase elevation. A poor prognostic sign

Edward J. Fudman*, Thomas J. Schnitzer

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

148 Scopus citations


Serum muscle enzyme levels are usually elevated in patients with untreated polymyositis and dermatomyositis. Creatine kinase is the muscle enzyme most often used to diagnose inflammatory myopathies. Seven patients with dermatomyositis and normal creatine kinase levels are described. Five of the seven patients had either an associated malignancy or severe interstitial lung disease. The one-year survival of the six patients followed for that length of time was 33 percent. A lack of creatine kinase elevation in patients with dermatomyositis is a poor prognostic sign.

Original languageEnglish (US)
Pages (from-to)329-332
Number of pages4
JournalThe American journal of medicine
Issue number2
StatePublished - Feb 1986

ASJC Scopus subject areas

  • Medicine(all)


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