Design and implementation of a highly selective minimal self-replicating system

Eleftherios Kassianidis; Douglas Philp

doi:10.1002/anie.200601845

Design and implementation of a highly selective minimal self-replicating system

Eleftherios Kassianidis^*, Douglas Philp

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

70 Scopus citations

Abstract

Self-direction: A rationally designed self-complementary template (see picture) is capable of replication, thereby amplifying itself from a reaction mixture to the exclusion of its diastereomer. This approach allows a highly selective amplification by focusing on templates that display a high level of complementarity to transition states. (Figure Presented).

Original language	English (US)
Pages (from-to)	6344-6348
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	45
Issue number	38
DOIs	https://doi.org/10.1002/anie.200601845
State	Published - Sep 25 2006

Keywords

Kinetics
Molecular modeling
Self-replication
Supramolecular chemistry
Template synthesis

ASJC Scopus subject areas

General Chemistry
Catalysis

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10.1002/anie.200601845

Cite this

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KW - Supramolecular chemistry

KW - Template synthesis

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Design and implementation of a highly selective minimal self-replicating system

Abstract

Keywords

ASJC Scopus subject areas

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