Design and Implementation of the Hispanic Community Health Study/Study of Latinos

Paul D. Sorlie*, Larissa M. Avilés-Santa, Sylvia Wassertheil-Smoller, Robert C. Kaplan, Martha L. Daviglus, Aida L. Giachello, Neil Schneiderman, Leopoldo Raij, Gregory Talavera, Matthew Allison, Lisa LaVange, Lloyd E. Chambless, Gerardo Heiss

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

514 Scopus citations


Purpose: The Hispanic Community Health Study (HCHS)/Study of Latinos (SOL) is a comprehensive multicenter community based cohort study of Hispanics/Latinos in the United States. Methods: The Study rationale, objectives, design, and implementation are described in this report. Results: The HCHS/SOL will recruit 16,000 men and women who self-identify as Hispanic or Latino, 18 to 74 years of age, from a random sample of households in defined communities in the Bronx, Chicago, Miami, and San Diego. The sites were selected so that the overall sample would consist of at least 2000 persons in each of the following origin designations: Mexican, Puerto Rican and Dominican, Cuban, and Central and South American. The study includes research in the prevalence of and risk factors for heart, lung, blood and sleep disorders, kidney and liver function, diabetes, cognitive function, dental conditions, and hearing disorders. Conclusions: The HCHS/SOL will (1) characterize the health status and disease burden in the largest minority population in the United States; (2) describe the positive and negative consequences of immigration and acculturation of Hispanics/Latinos to the mainstream United States life-styles, environment and health care opportunities; and (3) identify likely causal factors of many diseases in a population with diverse environmental exposures, genetic backgrounds, and early life experiences.

Original languageEnglish (US)
Pages (from-to)629-641
Number of pages13
JournalAnnals of Epidemiology
Issue number8
StatePublished - Aug 2010


  • Acculturation
  • Cardiovascular Disease
  • Epidemiologic Methods
  • Hispanics
  • Risk Factors

ASJC Scopus subject areas

  • Epidemiology


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