Detection of early cancer and pre-cancer with scattered light

L. T. Perelman*, V. Backman

*Corresponding author for this work

Research output: Contribution to journalConference article

1 Scopus citations

Abstract

The light scattering spectroscopy (LSS) of biological tissue aims to distinguish between single scattering from the cell structures such as cell nuclei located near the tissue surface and multiply scattered light (diffusive background). The spectrum of the single scattering component can be further analyzed to provide histological information about the uppermost cells, such as the size distribution of the cell nuclei. Experiments are presented which show that polarized LSS is capable of extracting morphological information from living cells in the presence of the large background from underlying tissue.

Original languageEnglish (US)
Pages (from-to)162-167
Number of pages6
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume4241
DOIs
StatePublished - Jan 1 2001
EventSaratov Fall Meeting 2000 Optical Technologies in Biophysics and Medicine II - Saratov, Russian Federation
Duration: Oct 3 2000Oct 6 2000

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

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