Detection of Kawasaki disease-associated antigen in inflamed gastrointestinal tract in acute Kawasaki disease

Masaru Miura*, Francesca L. Garcia, Susan E. Crawford, Anne H Rowley

*Corresponding author for this work

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

We performed immunohistochemistry experiments using synthetic antibodies on the gastrointestinal tract and kidney from acute Kawasaki disease patients. Significant gastrointestinal tract inflammation was present in only 2/7 patients, who had antigen detected at the site of inflammation. Antigen was not detected in kidney from 6 patients. The presence of antigen may be related to gastrointestinal pathology in acute Kawasaki disease.

Original languageEnglish (US)
Pages (from-to)927-929
Number of pages3
JournalPediatric Infectious Disease Journal
Volume24
Issue number10
DOIs
StatePublished - Jan 1 2005

Keywords

  • Gastrointestinal tract
  • Immunohistochemistry
  • Kawasaki disease
  • Kidney
  • Synthetic antibody

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

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