TY - JOUR
T1 - Developing a valid patient-reported outcome measure
AU - Rothrock, N. E.
AU - Kaiser, K. A.
AU - Cella, D.
PY - 2011/11
Y1 - 2011/11
N2 - Many aspects of patients' experiences with illness, medication, and health care are best captured from patient-reported outcomes (PROs). In this article, we describe the process for constructing quality PRO instruments, from conceptual model development through instrument validation. We also discuss PROs as clinical trial end points and the potential of PRO data for aiding clinicians and patients in choosing from among multiple therapeutic options. Finally, we provide an overview of some existing PRO instruments.
AB - Many aspects of patients' experiences with illness, medication, and health care are best captured from patient-reported outcomes (PROs). In this article, we describe the process for constructing quality PRO instruments, from conceptual model development through instrument validation. We also discuss PROs as clinical trial end points and the potential of PRO data for aiding clinicians and patients in choosing from among multiple therapeutic options. Finally, we provide an overview of some existing PRO instruments.
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U2 - 10.1038/clpt.2011.195
DO - 10.1038/clpt.2011.195
M3 - Article
C2 - 21975345
AN - SCOPUS:80054993653
SN - 0009-9236
VL - 90
SP - 737
EP - 742
JO - Clinical pharmacology and therapeutics
JF - Clinical pharmacology and therapeutics
IS - 5
ER -